Thought 56: A CRISPR Vaccine

Vaccines are designed to train our immune system to react to incoming virus and track component of their D/RNA. That information is generally stored inside cells inside our bone marrow. Current technology is that we find the virus break it apart and identify the piece that will trigger an immune response. What if we could change it up and simple put the information needed by the body direcctly into the storage cells? Could we take survivors of a disease and extra the DNA alterations stored in the bone marrow? Could we use that and build a CRISPR sequence that could be used to give immunity with needing to invoke an immunno response? Could end the need for endless vaccines in early childhood and start by modifying the immune system from the get go, many less injections? Could we accelerate future vaccines by already having this vetted and in place, so the time from initial infection to herd immunity basically drops to a few days?

We can use crispr for virus id. ref

We are planning things like stopping heart disease with CRiSPR: ref

Given current pandamic it is also noted that reinfections of C-19 is from damaged bone marrow, could this be the bypass? ref

It's also known that certain bone marrows can cure HIV/AIDs. It looks like they are already working on this angle as of 2015. ref

Is it possible? Or is this another useless thought?

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Thought 5 - The Ferengi of New Jersey

Just got back from a wedding in Jersey, and have determined that New Jersey has a lot going for it, and a lot of peculiarities to it as well. First the good: Mandatory recycling. Recycling is curb side and everything goes, this is a great benefit, as there are no third parties involved or hippies to worry about, everyone just recycles. Recycling also requires little effort on the user, plastic, glass, and metals all go in the same container, then paper products in another. Now the strange: Everyone drives everywhere, but there are lots of trees. Like a giant suburbia, where the trees have not yet been killed off by the logging industry. Now, having ridden my bike for most of my life, and having walked the dogs in the morning, I have become more aware of my sense of smell. And oddly New Jersey smells like conflict, the conflict between the cars trying to pollute the world and the trees absorbing that pollution and releasing oxygen. Quite and odd balance when the brain is in a toss...

Thought 16 - Kid Power

In response "Thought 14 - Perpetual Cat" sugarbumkin said, "The same theory could be applied to balloons tied to kindergarteners at recess. I like it." Well this got me thinking... Clothes with that are laced with MEMS generators. A MEMS generator is a solid state electronic circuit that generates low level of current though passive motion of the environment. Things like temperature change, acceleration, and even Brownian motion are converted to power using a MEMS generator. So, now we have attached them to small free moving bipeds of pure energy. How do we get the energy back. I figure that we isolate the playground into a large battery configuration where the children are running around on a conductive plate that makes contact with the heels of their shoes. They will run around with a super capacitor in addition to the MEMS, when their feet touch the ground the super-cap is discharged into the conductive plate underneath them. I do not think that the childr...

Thought 52: Coaster-less Beer Glass

It occurred to me last night while drinking beer that the coast was both irritating and waste of resources. Irritating that almost no glass actually lives on the coaster, preventing them from performing their original task of preventing damage to the table. And a waste that they get thrown away every night and in some cases every drink. So I dreamed up this: The glass has ridges to direct the condensation down to a reservoir at the bottom of the glass. The reservoir size will be base on the humidity and temperature difference of the beverage and the surrounding air. The reservoir can be drained by a couple of rubber plugs along the sides. The vary bottom of the glass is covered in a bit of rubber to prevent damaging the table from the hard glass. The interesting part is that the water will make the glass more stable as it is drunk by increasing the base weight. Cheers for your thoughts!

A Million Useless Thoughts

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